Even I know there are 2 splices to do on the '21, one of which does I suppose "reprogram" the PGM.
The M-max box may do nothing without one or either of these mods done (it does nothing on the NC35 anyway, and I speak from experience)
The first splice removes the retarding of the ignition at higher speeds, this is how the NSR was restricted to 113mph, there is no actual stopping it going faster like on the diesels, it just doesn't make enough power to get there as the timing gets wound back. This one is on the orange and blue wire on the pgm. This could definately be termed "reprogramming".
The second then tells it to use the more agressive third gear map for 4th, 5th and 6th. This is just a trick done on the GPS before it even gets to the PGM, the PGM then thinks the bike never leaves 3rd gear.
Without the 1st mod the 2nd one is useless as the power will still get rolled off.
It's all here
You can make 55 bhp or so with just the spices and some jetting easy, Andy's made 57bhp with his pipes and Monkey's carbs/std airbox as we played trying to get the mid range to work properly. I presume he's done both splices. Bills made 66bhp on std pipes.
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