Well the whole idea of the float is to open and close the valve as necessary, so setting it is done at the point where the needle just makes contact with the seat... this means as the fuel level rises to the set height, the needle shuts the flow off and the carb doesn't overflow!

So, yes the carb body should be pretty much horizontal (gasket face vertical/float pivot pin at the top/float hanging down), and then just tip the carb so the needle sits on the seat. You will notice there's a tiny sprung pin on the bottom of the needle; that shouldn't be compressed.
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Andy.
NSR-WORLD.COM

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